Effect of aqueous infusion of Plectranthus amboinicus (LOUR) Spreng leaves on humoral immune system in rats

نویسندگان

چکیده

Purpose: To examine the effect of an aqueous infusion Plectranthus amboinicus (AIP) on immunological development rats in response to Bacille Calmette-Guerin (BCG) antigen induction.
 Methods: Twenty-four male rats, aged 3 months, were separated into six groups. Group 1 was normal control group without treatment, whereas groups 2 and treatment induced with 100 μL BCG days 7 14, followed by oral administration AIP at doses 19 31.5 g/kg, respectively. Groups 4 5 treated only g/kg 6 a negative 14. On day 31, IgG activity, antibody titer, lysozyme relative organ weight, lung histology determined.
 Results: The results showed that levels, titers, activity significantly elevated 4, 5, compared (p < 0.05). Aqueous had no weight spleen. However, therapy administered increased their liver mass 0.05).
 Conclusion: leaves stimulates immune system BCG-induced rats.

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2023

ISSN: ['1596-5996', '1596-9827']

DOI: https://doi.org/10.4314/tjpr.v22i5.12